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When HGH supplements are used properly there are no adverse side effects. The only hgh side effects are when the supplements re abused and abused in connection with other substances abuse. For example if massive doses of HGH and steroids are used over a long period a variety of problems can show up. It is not certain which substance caused the actual negative side effect of it was the combination of substances abused that brought them about. I am sure more research will be done until conclusive evidence is obtained and these findings will be well published. At present there simply aren’t any documented negative hgh side effects to be found.